GMP Microspheres and Nanoparticles for Drug Encapsulation
SEM of ~4um Polymer/Drug Microspheres (3,500X)
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SEM of ~0.4um Polymer Nanospheres (5,000X)
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Biodegradable Drug Encapsulated Microspheres:
Medterials™ provides formulation development and pilot scale GMP manufacturing of biodegradable drug encapsulated microspheres.
Medterials microspheres are fabricated with a unique, proprietary process that provides a narrow particle size distribution to a desired mean diameter in the range of 2 to 50 microns. Available microspheres include:
Services include:
Biodegradable Drug Encapsulated Nanoparticles/Nanospheres:
Medterials nanoparticles are fabricated with a unique, proprietary process that provides a narrow particle size distribution in the submicron size range. Available nanoparticles include:
Services include:
Medterials™ provides formulation development and pilot scale GMP manufacturing of biodegradable drug encapsulated microspheres.
Medterials microspheres are fabricated with a unique, proprietary process that provides a narrow particle size distribution to a desired mean diameter in the range of 2 to 50 microns. Available microspheres include:
- PLGA microspheres
- PLA microspheres
- PLGA based tri polymer microspheres
- Small molecule drug encapsulation
- Batch testing includes particle size distribution, drug content, impurities, DSC
- Additional testing such as bioburden, particulate matter available through associated third party laboratories
Services include:
- Polymer selection/modification
- Polymer – Drug Composite Development
- Fabrication
- Material characterization
- Drug characterization, stability, elution rate
- Small scale GMP manufacturing to support clinical development
Biodegradable Drug Encapsulated Nanoparticles/Nanospheres:
Medterials nanoparticles are fabricated with a unique, proprietary process that provides a narrow particle size distribution in the submicron size range. Available nanoparticles include:
- PLGA nanoparticles
- PLA nanoparticles
- PLGA based tri polymer nanoparticles
- Surface modified PLGA and PLA nanoparticles
- Drug and biological agent encapsulation
- Batch testing includes particle size distribution, active agent content, impurities, polymer characterization
- Additional testing such as bioburden, particulate matter available through associated third party laboratories
Services include:
- Polymer selection/modification
- Polymer – Active Agent Composite Development
- Fabrication
- Nanoparticle characterization
- Active Agent characterization, stability
- Small scale GMP manufacturing to support clinical development